Cell Line Lysates
ABclonal Technology FABP5 Rabbit pAb
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.
Cayman Chemical IkarugamycIn 2.5mg
A macrocyclic antibiotic that exhibits cytotoxic effects in cancer cell lines, inhibiting cell proliferation (IC50 = 221.3 nM in HL-60 cells); 1-4 μM inhibits oxidized LDL-induced accumulation of cholesteryl esters in macrophages; inhibits clathrin-coated pit-mediated endocytosis
OriGene CD90 (THY1) (NM_006288) Human Untagged Clone, 10ug
THY1 (untagged)-Human Thy-1 cell surface antigen (THY1)
Cayman Chemical 7DeazaadenosIn5OtrIphos 2.5mg
A modified nucleotide and an active metabolite of tubercidin; incorporated into the DNA of mouse L-cells using DNA polymerase α but not into the RNA of E. coli using RdRps; has been used as a probe for the ATP binding site of PKA
Cayman Chemical LInarmycIn B 2.5mg
A polyene antibiotic; induces lysis and degradation of B. subtilis as a component of Streptomyces Mg1 extract
Cayman Chemical PenIcolInate B 2.5mg
A fungal metabolite with diverse biological activities; active against M. tuberculosis (MIC = 25 UG/ml), as well as P. falciparum, B. cereus, and C. albicans (IC50s = 1.4, 25, and 3.67 UG/ml, respectively); cytotoxic to MCF-7, KB, NCI H187, and Vero cells (IC50s = 6.21, 17.78, 0.307, and 2.79 UG/ml, respectively)
Cellular Engineering Technologies Cryopreserved vial of HepG2 hepatocellular carcinoma cells (500,000 cells)
HepG2 is a human cell line isolated from a liver biopsy of a 14-year-old male donor. HepG2 cells are used in a wide range of studies, from the oncogenesis to the cytotoxicity of substances in the liver.HepG2 cells have been used to study liver function broadly, including liver metabolism, cancer metastasis, and tumor formation. These cells secrete various major plasma proteins, including albumin, α2-macroglobulin, α1-anti-trypsin, and plasminogen.These cells can be used for (i) the study of carcinogenesis as a surrogate for liver toxicity, (ii) the analysis of signaling events, (iii) molecular biology, and (iv) protein-based assays. These immortalized hepatic cell lines can be used instead of biopsies for research purposes. These HepG2 cells are homogenous and grow robustly in cell culture. HepG2 cells grow slowly initially and grow in clusters rather than as an intact monolayer.Vial contains approximately 500,000 cells. Shipped with dry ice.
Macherey-Nagel MACHEREY-NAGEL Lysis Buffer LYS-EF, Endotoxin-Free Plasmid Isolation, Compatible With NucleoBond Xtra Kits, 1000 mL
The MACHEREY-NAGEL Lysis Buffer LYS-EF is designed for effective cell lysis in endotoxin-free plasmid DNA isolation, essential for high-quality DNA suitable for sensitive molecular biology applications. This buffer is particularly compatible with NucleoBond Xtra Midi and Maxi EF kits, setting it apart for its specialized formulation that meets rigorous research standards.
Lifeline Cell Technology STM CELLS MSC HU LIFELNE VL
HMSC-WJ and HMSC-Ad can be expanded in an undifferentiated state for future differentiation to multiple lineages. May be differentiated down the typical mesenchymal lineages, such as adipogenic, chondrogenic, and osteogenic lineages.
ABclonal Technology SCN1B Rabbit pAb
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
Cayman Chemical Mouse Macrophage Microsomal I
Cyclooxygenase 2 (COX-2) is a 72 kDa protein that has been cloned from a variety of species including human, mouse, rat, and ovine. This preparation of COX-2 microsomes was prepared by solubilization and dilution of the 100,000 x g pellet from the lysate of cytokine-stimulated mouse macrophage cultures. Cayman’s preparation of mouse macrophage microsomes is a ready-to-use sample for SDS-PAGE. As such, it is an excellent positive control for the following Cayman Chemical polyclonal antibodies: Item Nos. 160106, 160126, 160116, and 101750.
ABclonal Technology CREB3L2 Rabbit pAb
This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene.